Genetic explanation for Chinese woman ovarian reserve problem

Novel WT1 Missense Mutations in Han Chinese Women with Premature Ovarian Failure Scientific Reports 5, Article number: 13983 (2015) Abstract Premature ovarian failure (POF) is a heterogeneous disease. Though dozens of candidate genes have been identified for the genetic etiology of POF, it is largely unexplained in majority of patients. Recently,Wt1+/R394W mice was found to present POF-like…